Central directions for reducing cardiovascular mortality: what can be changed today?

Molecular imaging: what can be used today

Biochemical cellular targets and more general metabolic processes in cancer cells can be visualised. Extensive data are available on molecular imaging in preclinical models. However, innovative tracers move slowly to the clinic. This review provides information on the currently available methods of metabolic imaging, especially using PET in humans. The uptake mechanisms of tracer methods and a ...

“Not Everything That Is Faced Can Be Changed, but Nothing Can Be Changed Until It Is Faced”: A Response to Recent Commentaries

Reducing mortality in sepsis: new directions

Considerable progress has been made in the past few years in the development of therapeutic interventions that can reduce mortality in sepsis. However, encouraging physicians to put the results of new studies into practice is not always simple. A roundtable was thus convened to provide guidance for clinicians on the integration and implementation of new interventions into the intensive care uni...

Reducing landmine mortality rates in Iran using public medical education and rural rescue teams--what can be learned from landmine casualties, and how can the situation be improved?

Landmines and unexploded ordnance pose a significant international public health risk and economic threat. Worldwide, an estimated 60 to 110 million anti-personnel landmines have been placed in >70 countries. According to UN sources, as many as two million new mines are laid every year, but due to the high cost of removal, only 200,000 mines are defused each year. Landmines pose a serious ongoi...

What changes in inflammatory bowel disease management can be implemented today?

Innovative ideas are required to improve the management of inflammatory bowel disease and to share best practice that can be implemented into clinical practice today. The use of biomarkers such as calprotectin to monitor disease progression and treatment response could help to improve management of inflammatory bowel disease, but several strategies need to be implemented to make this a reality ...